大腸直腸癌治療(健保給付規定) :Capacitabine（如Xeloda）截瘤達

Capecitabine（如Xeloda）截瘤達

1. 治療轉移性結腸直腸癌的第一線用藥。（92/6/1）
2. 第三期結腸癌患者手術後的輔助性療法，以八個療程為限。（96/9/1）

參考資料: 全民健康保險藥品給付規定

Reference

CapOx
1. Cassidy J et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol 2008; 26:2006   

2. Diaz-Rubio E et al. Phase III study of capecitabine plus oxaliplatin compared with continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol 2007; 25:4224

3. Hochster, HS et al. Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE Study. J Clin Oncol 2008; 26:3523

4. Porschen R et al. Phase III study of capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin in metastatic colorectal cancer: a final report of the AIO Colorectal Study Group. J Clin Oncol 2007; 25:4217

Adjuvant Capacitabine
1.Twelves C et al. Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med 2005; 352:2696